Tissue Disease

Name of disease 
Kindler Syndrome (Type of Epidermolysis Bullosa)


Symptoms

• Fluid-filled blisters on the skin, especially on the hands and feet due to friction

• Deformity or loss of fingernails and toenails

• Internal blistering, including on the vocal cords, esophagus and upper airway

• Skin thickening on the palms and the soles of the feet

• Scalp blistering, scarring and hair loss (scarring alopecia)

• Thin-appearing skin (atrophic scarring)

• Tiny white skin bumps or pimples (milia)

• Dental problems, such as tooth decay from poorly formed enamel

• Difficulty swallowing (dysphagia)

Prognosis
Life expectancy is normal.

Treatments
Esophageal strictures can be treated by balloon dilatation with fluoroscopic guidance.

Picture

Reference

• http://www.medicinenet.com/epidermolysis_bullosa_eb/article.htm 

• http://www.mayoclinic.org/diseases-conditions/epidermolysis-bullosa/basics/causes/con-20032497

• http://emedicine.medscape.com/article/1118967-overview

• http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=2908